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Structural analysis is the determination of the effects of loads on physical structures and their components.
Structures subject to this type of analysis include all that must withstand loads, such as buildings, bridges, vehicles, machinery, furniture, attire, soil strata, prostheses and biological tissue.
Age-related macular degeneration (AMD) affects 9 million older Americans, and is characterized by the loss of the retinal pigment epithelium (RPE).
Although the closely linked genome-wide association studies genes, located at the chromosome 10q26 locus, are strongly associated with the risk of AMD, their downstream targets are unknown.
The polymerase complex within the core then synthesizes transcripts from each genome segment and extrudes these into the cytoplasm where they act as templates for protein synthesis.Low population frequencies of risk alleles in tissue banks make it impractical to study their function in cells derived from autopsied tissue.Moreover, autopsy eyes from end-stage AMD patients, where age-related RPE atrophy and fibrosis are already present, cannot be used to determine how abnormal expression can initiate RPE pathology.A computer network, often simply referred to as a network, is a collection of hardware components and computers interconnected by communication channels that allow sharing of resources and information.Where at least one process in one device is able to send/receive data to/from at least one process residing in a remote device, then the two devices are said to be in a network.
Newly synthesized ss RNA then associates with the replicase complex prior to encapsidation by inner and outer protein layers of core within virus-triggered inclusion bodies.